STING Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA526751
DescriptionActs as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
|KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human TM173|
|Protein A, Antigen Affinity Chromatography|
|Flow Cytometry, Western Blot|
|PBS with 0.09% sodium azide|
|ERIS, MITA, MPYS, NET23, STING, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, endoplasmic reticulum IFN stimulator, endoplasmic reticulum interferon stimulator, hMITA, hSTING, mediator of IRF3 activation, mitochondrial mediator of IRF3 activation, stimulator of in|
|-20° C, Avoid Freeze/Thaw Cycles|
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