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TMEM16B Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520842

Catalog No. PIPA520842


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Description

Description

A suggested positive control is rat brain tissue lysate. PA5-20842 can be used with blocking peptide PEP-0956.

Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC’s include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC’s but has different biophysical characteristics such as voltage dependence and unitary conductance.
Specifications

Specifications

TMEM16B
Polyclonal
Unconjugated
ANO2
Liquid
ANO2
A 19 amino acid peptide from near the amino terminus of human TMEM16B.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9NQ90, Q8CFW1
C12orf3, TMEM16B; anoctamin-2; transmembrane protein 16B (eight membrane-spanning domains)
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
100361584, 243634, 57101
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