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TMEM66 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524237

Catalog No. PIPA524237


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Description

Description

Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.
Specifications

Specifications

TMEM66
Polyclonal
Unconjugated
SARAF
Liquid
SARAF
KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human TMEM66
Protein A, Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Flow Cytometry, Western Blot
0.3 mg/mL
PBS with 0.09% sodium azide
Q96BY9, Q8R3Q0
FOAP-7, XTP3, HBV X-transactivated gene 3 protein, HBV XAg-transactivated protein 3, protein FOAP-7
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
51669, 67887
Documents
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