TMEM66 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524237
DescriptionSaraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.
|KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human TMEM66|
|Protein A, Antigen Affinity Chromatography|
|Flow Cytometry, Western Blot|
|PBS with 0.09% sodium azide|
|FOAP-7, XTP3, HBV X-transactivated gene 3 protein, HBV XAg-transactivated protein 3, protein FOAP-7|
|-20° C, Avoid Freeze/Thaw Cycles|
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