MilliporeSigma anti-TMPRSS2 Clone: 2F4,
Mouse Monoclonal Antibody
Manufacturer: MilliporeSigma ST1676100UG
Specifically detects TMPRSS2 Clone: 2F4 in Human samples, and it is validated for ELISA, Immuno BlottingThis gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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|In PBS, pH 7.2.|
|Recognizes the TMPRSS2 protein.|
|ELISA, Immuno Blotting, Immunoblot|
|A recombinant polypeptide corresponding to amino acids of 383-493 human TMPRSS2, expressed as a GST fusion protein|
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