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TNIP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141174

Catalog No. 01-675-745


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Description

Description

Suggested positive control: antigen standard for TNIP2 (transient overexpression lysate), mouse heart or lung tissue, mouse heart protein.

ABIN-2, TNFAIP3 interacting protein 2, binds to the COOH-terminal zinc finger domain of A20. NF-kB activation induced by TNF and interleukin-1 is inhibited by overexpression of ABIN-2. The latter also inhibits NF-kB activation induced by overexpression of receptor-interacting protein or TNF receptor-associated factor 2. A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB)Activation (ABIN-2) binds to A-20. ABIN-2 interferes with NF-kB activation upstream of the IKK complex and might contribute to NF-kB inhibitory function of A-20.
Specifications

Specifications

TNIP2
Polyclonal
Unconjugated
TNIP2
Liquid
TNIP2
Synthetic peptide corresponding to a portion of human ABIN-2.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q8NFZ5, Q99JG7
TNFAIP3-interacting protein 2, FLIP1, Fetal liver LKB1-interacting protein
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
231130, 305451, 79155
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