CD267 (TACI) Mouse anti-Human, Clone: 165609, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523781
In direct ELISAs and Western blots, no cross-reactivity with Recombinant mouse TACI or Recombinant human BCMA is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
|PBS with 5% trehalose and No Preservative|
|CD267, CVID, CVID2, TACI, TNFRSF14B, transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B, tumor necrosis factor receptor superfamily member 13B|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunohistochemistry, Neutralization, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human TACI/TNFRSF13B Ser2-Thr166|
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