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CD267 (TACI) Mouse anti-Human, Clone: 165609, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523879

Catalog No. PIMA523879


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Description

Description

In direct ELISAs and Western blots, no cross-reactivity with recombit mouse TACI or recombit human BCMA is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Specifications

Specifications

CD267 (TACI)
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O14836
CD267, CVID, CVID2, TACI, TNFRSF14B, transmembrane activator and CAML interactor, tumor necrosis factor receptor 13B, tumor necrosis factor receptor superfamily member 13B
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
23495
ELISA, Immunohistochemistry, Neutralization, Western Blot
165609
Unconjugated
TNFRSF13B
Lyophilized
TNFRSF13B
Mouse myeloma cell line NS0-derived recombit human TACI/TNFRSF13B Ser2-Thr166
Protein A/G
RUO
Antibody
Monoclonal
Human
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