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TOPORS Mouse anti-Human, Clone: 4G4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA520967

Catalog No. PIMA520967


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Description

Description

Peptide Sequence: SPDSKCPICL DRFDNVSYLD RCLHKFCFRC VQEWSKNKAE CPLCKQPFDS IFHSVRAEDD FKEYVLRPSY NGSFVTPDRR FRYRTTLTRE RNASVYSPSG PVNRRTTT

Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.
Specifications

Specifications

TOPORS
Monoclonal
0.5 mg/mL
PBS with no preservative; pH 7.4
Q9NS56
TOPORS
TOPORS (NP_005793, 98 a.a. ∽ 205 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
4G4
Unconjugated
TOPORS
Liquid
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
10210
Documents
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