TOPORS Mouse anti-Human, Clone: 4G4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA520967
Peptide Sequence: SPDSKCPICL DRFDNVSYLD RCLHKFCFRC VQEWSKNKAE CPLCKQPFDS IFHSVRAEDD FKEYVLRPSY NGSFVTPDRR FRYRTTLTRE RNASVYSPSG PVNRRTTTFunctions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.
|PBS with no preservative; pH 7.4|
|TOPORS (NP_005793, 98 a.a. ∽ 205 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|-20° C, Avoid Freeze/Thaw Cycles|
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