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TPSD1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524002

Catalog No. PIPA524002

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3 ft. UTR and contain tandem repeat sequences at the 5 ft. flank and 3 ft. UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.
Specifications

Specifications

TPSD1
Polyclonal
Unconjugated
TPSD1
Liquid
TPSD1
KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human TPSD1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
Q9BZJ3
MCP7-LIKE, MCP7L1, MMCP-7L, delta-tryptase, hmMCP-3-like tryptase III, mMCP-7-like delta II tryptase, mMCP-7-like-1, mMCP-7-like-2, mast cell tryptase, tryptase delta, tryptase-3
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23430
Documents
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