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TAAR1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen OSR00079W

Catalog No. PIOSR00079W


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Description

Description

Reconstitute with 100 µL of distilled water. Centrifuge to remove any insoluble material. OSR00079W can be used with blocking peptide GST00001P.

Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestin. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle, and spleen.
Specifications

Specifications

TAAR1
Polyclonal
whole serum with no preservative
Q96RJ0
Trace amine receptor 1, TaR-1, TA1, TAR1, TRAR1
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Western Blot
Unconjugated
TAAR1
Lyophilized
TAAR1
A synthetic peptide from human TAAR1 conjugated to an immunogenic carrier Protein
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
134864
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