TAAR1 Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141477
DescriptionTAAR1 is a 339 amino acid novel membrane protein belonging to the G protein-coupled receptor family and is activated by a broad range of monoamines and amphetamine-related psychostimulants (biogenic amines). It has two N-glycosylation sites at its N terminus and several potential protein kinase sites at its C terminus, including two serines and a single disulfide bridge. It shows lower cAMP accumulation in response to octopamine, tryptamine, dopamine and unresponsive to the classical biogenic amines norepinephrine, serotonin, and histamine. It is also known to have a chemosensory function distinct from odorant receptors and is involved in functional regulation of DAT and is a potentially important target for therapeutics for methamphetamine addiction. Recent studies demonstrated wide distribution of TAAR1 in brain.
|Synthetic peptide corresponding to residues 200-230 of human TAAR1.|
|Human, Non-human primate|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% sodium azide|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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