Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MilliporeSigma™ anti-TRAF6, Polyclonal, ™ Non-distribution product as customer accommodation.

Manufacturer:  MilliporeSigma™ 061110/DEL

Catalog No. 50-171-969

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
View substitute products »


Description

Description

TNF receptor-associated factor 6 is a member of the TNF receptor associated factor (TRAF) protein family. TNF receptor-associated factor 6 proteins play an important role as adaptor protein for cell survival, proliferation, differentiation and stress responses. TNF receptor-associated factor 6 has unique binding behavior that result in signaling responses from the interleukin-1 receptor (IL-1R) toll-like receptor. TNF receptor-associated factor 6 mediates signaling indirectly with IL-1R/TLR through IRAK. This leads to activation of NF-κB and MAP kinase signaling pathways though downstream association with the TAB/TAK-1 complex. TNF receptor-associated factor 6 is also involved in the activation of Akt/PKB and serves as a direct E3 ligase which is essential for Akt ubiquitination.

Host Species: Rabbit
Cross Reactivity: Equine, Human, Rhesus Ma
Immunogen: KLH-conjugated linear peptide corresponding to the MATH (meprin-associated Traf homology) domain of human TRAF6.

Immunohistochemistry, Western Blotting

Specifications

Specifications

TRAF6
Purified
KLH-conjugated linear peptide corresponding to the MATH (meprin-associated Traf homology) domain of human TRAF6.
Primary
Equine, Human, Rhesus
Unconjugated
Rabbit
100μg
Polyclonal
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit