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TRAG3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112867

Catalog No. 01-675-847


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Description

Description

This protein is expressed in various tumor cell lines including carcinomas, myeloid or lymphoid maligcies, melanomas or prostate cancer. It is also weakly expressed in kidney and overexpressed in taxol-resistant breast cancer line MDA 435(TR) or the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) or 8226/MDR(10)V.1.

The expression of the cancer-testis antigen Taxol resistanceassociated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxolresistant breast cancer line MDA 435(TR) and the doxorubicinresistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR (10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer.
Specifications

Specifications

TRAG3
Polyclonal
PBS with 0.08% sodium azide
Q9Y5P2
CSAG3B, CT24.2, MGC149851, MGC149852, TRAG3
Rabbit
IgG
50 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
102723547
Western Blot
Unconjugated
CSAG2
Liquid
CSAG2
Synthetic peptide corresponding to human Trag-3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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