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TRAG3 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA112868
This protein is expressed in various tumor cell lines including carcinomas, myeloid or lymphoid maligcies, melanomas or prostate cancer. It is also weakly expressed in kidney and overexpressed in taxol-resistant breast cancer line MDA 435(TR) or the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) or 8226/MDR(10)V.1.The expression of the cancer-testis antigen Taxol resistanceassociated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxolresistant breast cancer line MDA 435(TR) and the doxorubicinresistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR (10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer.
|PBS with 0.08% sodium azide|
|CSAG3B, CT24.2, MGC149851, MGC149852, TRAG3|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|Synthetic peptide corresponding to human Trag-3.|
|Ammonium sulfate precipitation|
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