TRAIL Mouse anti-Human, Clone: 124723, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523771
Reconstitute at 0.5 mg/mL in sterile PBS.Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand) (6,7). TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.
|PBS with 5% trehalose and No Preservative|
|Apo2L, Apo-2 Ligand, TNF-Related Apoptosis-Inducing Ligand, Tumor necrosis factor ligand, superfamily member 10, TRAIL protein, CD253 antigen, TNFSF10|
|-20° C, Avoid Freeze/Thaw Cycles|
|E. coli-derived recombit human TRAIL Val114-Gly281|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok