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DR4 Mouse anti-Human, Clone: DR-4-02, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119025

Catalog No. 01-674-998


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Description

Description

Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
Specifications

Specifications

DR4
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.4
O00220
APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
8797
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunoprecipitation
DR-4-02
Unconjugated
TNFRSF10A
Liquid
TNFRSF10A
Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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