CD264 (TRAIL-R4) Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14298
PA1-4298 detects the TRAIL-Receptor 4 protein in human samples. PA1-4298 has been successfully used in Western blot procedures. PA1-4298 immunogen corresponds to a.a. 57-73 of the mature human TRAIL-R4 protein.TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
|Synthetic peptide: T(57) I P R Q D E V P Q Q T V A P Q Q(73)|
|Antigen affinity chromatography|
|PBS with 0.02% sodium azide|
|CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD, TRAIL receptor 4|
|-20° C, Avoid Freeze/Thaw Cycles|
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