anti-Transferrin Receptor/CD71 Clone: H68.4, Thermo Scientific™ Novex™ Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.

Transferrin Receptor/CD71 Monoclonal antibody 13-6800 from Thermo Scientific™ Novex™ specifically detects Transferrin Receptor/CD71 in Chicken, Hamster, Mouse and Rat samples, and it is validated for WB, IF, IHC (P), FACS, IP, ELISA and IM

Manufacturer: Invitrogen 136800

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Catalog No. 13-680-0

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    Antigen Transferrin Receptor/CD71
    Clone H68.4
    Conjugate Unlabeled
    Cross Reactivity Chicken,Hamster,Mouse,Rat
    Format Affinity Purified
    Formulation 100μg of Affinity chromatography antibody in PBS with 0.1% sodium azide; pH 7.4.
    Gene Accession No. Q62351, Q90997, Q99376
    Host Species Mouse
    Immunogen Recombinant human transferrin receptor.
    Isotype IgG1
    Purification Method Affinity chromatography
    Storage Requirements Store at -20°C
    Primary or Secondary Primary
    Monoclonal or Polyclonal Monoclonal
    Gene ID (Entrez) 22042, 396191, 64678

    CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
    Host Species: Mouse
    Cross Reactivity: Chicken, Hamster, Mouse, Rat
    Isotype: IgG1
    Clone: H68.4
    Immunogen: Recombinant human transferrin receptor.
    Formulation: 100µg purified antibody in PBS and 0.1% sodium azide; pH 7.4
    Synonyms: CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
    Uniprot Accession: Q62351, Q90997, Q99376
    Entrez GeneID: 22042, 396191, 64678
    Gene Symbol: TFRC
    This product detects Transferrin Receptor/CD71 in Chicken, Hamster, Mouse and Rat samples. This product has been successfully used in ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation and Western Blot procedures. The immunogen is Recombinant human transferrin receptor..
    Test: ICC, Dilution: 1:500, Species: Ms, Reference: Automated analysis of neuronal morphology, synapse number and synaptic recruitment. (Feb 2011) J. Neurosci. Methods, Vol: 195, 2, 185-93, Schmitz SK,Hjorth JJ,Joemai RM,Wijntjes R,Eijgenraam S,de Bruijn P,Georgiou C,de Jong AP,van Ooyen A,Verhage M,Cornelisse LN,Toonen RF,Veldkamp WJ,Veldkamp W; Pubmed ID: 21167201

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