Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

TGM2 Mouse anti-Human, Clone: 14G2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen LFMA0094

Catalog No. AML0094


Add to cart

Description

Description

A suggested positive control for this product is U87-MG cells.

Transglutaminase (TGase) catalyses the crosslink of proteins by forming e-(g-glutamyl) lysine isopeptide bonds and requires the binding of Ca2+ for its activity. In mammals, eight distinct TGase isoenzymes have been identified. Tissue transglutaminase (tTGase), also known as TGase 2, has four distinct domains: N-terminal b-sandwich, catalytic core and two C-terminal b-barrel domains. tTGase may have a role in cell death, cell proliferation, cell differentiation, and receptor-mediated endocytosis. In the Alzheimer ft.s disease brain, the elevated tTGase activity is manifested by polymerization of a number of proteins, including Ab peptide, b-amyloid precursor protein and the tau protein, with formation of neurofibrillary tangles.
Specifications

Specifications

TGM2
Monoclonal
2 mg/mL
HEPES with 0.01% BSA, 0.15M NaCl, 50% glycerol and 0.03% sodium azide
P21980
C polypeptide, G alpha h, G protein alpha subunit Gh class,
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7052
ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
14G2
Unconjugated
TGM2
Liquid
TGM2
Purified, recombit, human transglutaminase 2 protein expressed in E. coli.
Protein G
RUO
Antibody
Monoclonal
Human
SDS
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit