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TGM2 Mouse anti-Human, Clone: 14G2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen LFMA0094
Description
A suggested positive control for this product is U87-MG cells.
Transglutaminase (TGase) catalyses the crosslink of proteins by forming e-(g-glutamyl) lysine isopeptide bonds and requires the binding of Ca2+ for its activity. In mammals, eight distinct TGase isoenzymes have been identified. Tissue transglutaminase (tTGase), also known as TGase 2, has four distinct domains: N-terminal b-sandwich, catalytic core and two C-terminal b-barrel domains. tTGase may have a role in cell death, cell proliferation, cell differentiation, and receptor-mediated endocytosis. In the Alzheimer ft.s disease brain, the elevated tTGase activity is manifested by polymerization of a number of proteins, including Ab peptide, b-amyloid precursor protein and the tau protein, with formation of neurofibrillary tangles.Specifications
TGM2 | |
Monoclonal | |
2 mg/mL | |
HEPES with 0.01% BSA, 0.15M NaCl, 50% glycerol and 0.03% sodium azide | |
P21980 | |
C polypeptide, G alpha h, G protein alpha subunit Gh class, | |
Mouse | |
IgG1 | |
100 μL | |
-20° C, Avoid Freeze/Thaw Cycles | |
Primary | |
7052 |
ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
14G2 | |
Unconjugated | |
TGM2 | |
Liquid | |
TGM2 | |
Purified, recombit, human transglutaminase 2 protein expressed in E. coli. | |
Protein G | |
RUO | |
Antibody | |
Monoclonal | |
Human |
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