Transthyretin Mouse anti-Human, Clone: 10E1, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific LFMA0174

Catalog No. LFMA0174

Description

A suggested positive control for this product is human plasma.

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predomitly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Specifications

• Antigen: Transthyretin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Gene: TTR
• Gene Alias: HsT2651, PALB, TBPA
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 7276
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Clone: 10E1
• Conjugate: Unconjugated
• Gene Accession No.: P02766
• Gene Symbols: TTR
• Immunogen: Recombit human protein purified from E.coli
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a