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Transthyretin Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527220

Catalog No. PIPA527220


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Description

Description

PA5-27220 targets Transthyretin in WB applications and shows reactivity with mouse samples. The PA5-27220 immunogen is recombit fragment corresponding to a region within amino acids 1 and 147 of Human Transthyretin. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predomitly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
Specifications

Specifications

Transthyretin
Polyclonal
Unconjugated
TTR
Liquid
TTR
Recombit fragment corresponding to a region within amino acids 1 and 147 of Human Transthyretin
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P02766, P07309
CTS, CTS1, HsT2651, PALB, TBPA, ATTR, carpal tunnel syndrome 1, prealbumin, amyloidosis type I, thyroxine-binding prealbumin
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22139, 7276
Documents
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