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Transthyretin Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA520742

Catalog No. PIPA520742


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Description

Description

A suggested positive control is human lung tissue lysate. PA5-20742 can be used with blocking peptide PEP-0856.

Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predomitly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintece of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson’s disease, schizophrenia, and depression.
Specifications

Specifications

Transthyretin
Polyclonal
Unconjugated
TTR
Liquid
TTR
A 17 amino acid peptide near the center of human Transthyretin.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P02766, P07309, P02767
CTS, CTS1, HsT2651, PALB, TBPA; ATTR; carpal tunnel syndrome 1; prealbumin, amyloidosis type I; thyroxine-binding prealbumin
Chicken
IgY
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
22139, 24856, 7276
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