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TRBP1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520331

Catalog No. PIPA520331


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Description

Description

A suggested positive control is NIH-3T3 cell lysate. PA5-20331 can be used with blocking peptide PEP-0451.

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
Specifications

Specifications

TRBP1
Polyclonal
Unconjugated
TARBP1
Liquid
TARBP1
A 17 amino acid peptide from near the center of human TRBP1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q13395
RP5-827C21.5, TRM3, TRP-185, TRP185; TAR (HIV) RNA binding protein 1; TAR (HIV) RNA-binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; probable methyltransferase TARBP1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
212728, 6894
Documents
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