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KCNK2 Rabbit anti-Bovine, Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA116981

Catalog No. 01-670-158


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Description

Description

This antibody is 88% homologous to rat. It is not recommended for ICC/IF or Immunohistochemistry applications.

TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. As well, it is regulated by various neurotransmitters. It has been shown that alterations in the functioning, regulation, or both of the TREK-1 channel may alter mood. TREK-1 is also activated by volatile anesthetics and has been suggested to be an important target in the action of these drugs. Therefore, this particular K+ channel emerges as a potential innovative target for developing new therapeutic agents for anesthesiology and neurology, such as antidepressants.
Specifications

Specifications

KCNK2
Polyclonal
Unconjugated
KCNK2
Liquid
KCNK2
Synthetic peptide within the N-terminal region (residues 1-100) of human TREK 1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Human, Mouse
Western Blot
1 mg/mL
tris glycine with 0.15M NaCl and 0.05% sodium azide
O95069, P97438
Two-pore domain potassium channel TREK-1 antibody; Potassium channel, subfamily K, member 2 antibody; Twik-Related K+ Channel 1 antibody; Kcnk2 antibo
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
16526, 282590, 3776
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