KCNK2 Rabbit anti-Bovine, Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA116981
This antibody is 88% homologous to rat. It is not recommended for ICC/IF or Immunohistochemistry applications.TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. As well, it is regulated by various neurotransmitters. It has been shown that alterations in the functioning, regulation, or both of the TREK-1 channel may alter mood. TREK-1 is also activated by volatile anesthetics and has been suggested to be an important target in the action of these drugs. Therefore, this particular K+ channel emerges as a potential innovative target for developing new therapeutic agents for anesthesiology and neurology, such as antidepressants.
|Synthetic peptide within the N-terminal region (residues 1-100) of human TREK 1.|
|Antigen affinity chromatography|
|Bovine, Human, Mouse|
|tris glycine with 0.15M NaCl and 0.05% sodium azide|
|Two-pore domain potassium channel TREK-1 antibody; Potassium channel, subfamily K, member 2 antibody; Twik-Related K+ Channel 1 antibody; Kcnk2 antibo|
|-20° C, Avoid Freeze/Thaw Cycles|
|16526, 282590, 3776|
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