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TREX1 Mouse anti-Human, Clone: 1B1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521323

Catalog No. PIMA521323


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Description

Description

Peptide Sequence: MGPGARRQGR IVQGRPEMCF CPPPTPLPPL RILTLGTHTP TPCSSPGSAA GTYPTMGSQA LPPGPMQTLI FFDMEATGLP FSQPKVTELC LLAVHRCALE

This gene encodes the major 3 ft.->5 ft. DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3 ft. ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

TREX1
Monoclonal
0.5 mg/mL
PBS with no preservative; pH 7.4
Q9NSU2
AGS1, CRV, DRN3, HERNS; 3′ repair exonuclease 1; 3′-5′ exonuclease TREX1; DNase III
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11277
ELISA, Western Blot
1B1
Unconjugated
TREX1
Liquid
TREX1
TREX1 (NP_057465, 1 a.a. ∽ 100 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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