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three prime repair exonuclease 1, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human TREX1 protein.

Manufacturer:  Abnova Corporation H00011277B02

Catalog No. 89-007-179


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Description

Description

This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a nonprocessive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: MGPGARRQGRIVQGRPEMCFCPPPTPLPPLRILTLGTHTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE
Specifications

Specifications

three prime repair exonuclease 1
Unconjugated
No additive
NM_016381
AGS1|AGS5|CRV|DKFZp434J0310|DRN3|HERNS
Mouse
50 uL
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Primary
11277
Western Blot
Mouse polyclonal antibody raised against a full-length human TREX1 protein.
TREX1
Serum
TREX1
TREX1 (NP_057465, 1 a.a. ~ 369 a.a) full-length human protein.
RUO
Y
Polyclonal
Human
SDS
Documents
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