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TRF2 Goat anti-Human, Mouse, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA141023

Catalog No. 01-676-637


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Description

Description

Suggested positive control: antigen standard for TERF2 (transient overexpression lysate), Daudi, HeLa, HL-60, or Jurkat.

TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length (1). TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes (2). TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini (2). The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells (2). Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types (3).
Specifications

Specifications

TRF2
Polyclonal
Unconjugated
TERF2
Liquid
TERF2
Baculovirus expressed His-tagged whole length TRF2 protein.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse
ChIP assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
1 mg/mL
PBS with 0.05% sodium azide
Q15554, O35144
TRBF2, TRF2
Goat
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
21750, 7014
Documents
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