TRHR Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527078
PA5-27078 targets TRHR in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27078 immunogen is synthetic peptide corresponding to a region within amino acids 287 and 383 of Human TRHR. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Thyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.
|Synthetic peptide corresponding to a region within amino acids 287 and 383 of Human TRHR|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|TRH-R, thyroliberin receptor|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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