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Tri-Methyl-Histone H3 (Lys4) Rabbit anti-Human, Many, Mouse, Plant, Zebrafish, Polyclonal, Invitrogen™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen 491005

Catalog No. 49-100-5


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Description

Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post tranlationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications

Specifications

Tri-Methyl-Histone H3 (Lys4)
Polyclonal
Unconjugated
HIST1H3A
Liquid
HIST1H3A
Raised against the region of the histone H3 containing the trimethylated lysine 4 (or [K4me3]), using a KLH-conjugated synthetic peptide.
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Many, Mouse, Plant, Zebrafish
ChIP assay, ChIP-sequencing, ELISA, Immunocytochemistry, Immunofluorescence, Peptide Array, Western Blot
1.4 mg/mL
PBS with 0.05% Proclin 300, 0.05% sodium azide
P68431, P68433
H3K4me3, Histone H3, Histone 1, H3a, Histone H3.1, histone H3/a, HIST1H3A
Rabbit
IgG
50 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
360198, 8350
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