Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

RNF216 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141317

Catalog No. 01-675-654


Add to cart

Description

Description

Suggested positive control: human spleen protein, antigen standard for RNF216 (transient overexpression lysate), human lung protein, human ovary protein, human pancreas protein, human skeletal muscle protein, human heart protein, human kidney protein, human liver protein, human brain protein, human brain tissue, heart tissue, kidney tissue, liver tissue, lung tissue, ovary tissue, pancreas tissue, small intestine tissue, skeletal muscle tissue, spleen tissue, human small intestine protein.

Principal Names: TRIAD3; E3-Ubiquitin Ligase TRIAD3; U7I1; ZIN; Zinc finger protein inhibiting NF-kappaB; Ubiquitin conjugating enzyme 7 interacting protein 1; UBCE7IP1; Official Gene Symbol: TRIAD3 Gene ID: 54476 (Human) Gene Map Locus: 7p22.1 (Human) TRIADs are novel zinc finger proteins characterized by the presence of Cysteine rich TRIAD domain consisting of DRIL motif flanked by 2 RING fingers. TRIAD3, a 56KDa protein, is a novel member of this family. It contains 4 RLD domains in the centre and a proline-rich domain at the C-terminus. Localized in the cytoplasm, it interacts with RIP and inhibits TNF and IL1-induced NF-kappaB activation pathways. Reports suggest TRIAD3 acts as an E3-ubiquitin-protein ligase and promotes ubiquitination and degradation of TLR4 and TLR9, thereby regulating TLR signaling. It also interacts with HIV type I Vif protein and interferes in the early events of HIV-1 replication.
Specifications

Specifications

RNF216
Polyclonal
Unconjugated
RNF216
Liquid
RNF216
Synthetic peptide corresponding to residues 350-400 of human TRIAD3A.
Protein G
RUO
Antibody
Polyclonal
Human
Western Blot
0.5 mg/mL
PBS with 0.2% gelatin and 0.05% sodium azide
Q9NWF9
TRIAD3, U7I1, UBCE7IP1, ZIN
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
54476
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit