TRIM5 alpha Goat anti-Human, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA518466
This antibody is predicted to react with human based on sequence homology.The protein encoded by this gene is a member of the tripartite motif family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
|Synthetic peptide sequence (CNIEKNENYQPK) corresponding to the internal amino acids of TRIM5|
|Antigen affinity chromatography|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|TRIM5; tripartite motif-containing 5 ; HGNC:16276; RNF88; tripartite motif protein 5; tripartite motif protein TRIM5; TRIM5alpha; OTTHUMP00000069812; tripartite motif protein TRIM; tripartite motif-containing protein 5 alpha|
|-20° C, Avoid Freeze/Thaw Cycles|
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