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TRIP6 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521040

Catalog No. PIPA521040


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Description

Description

A suggested positive control is EL4 cell lysate. PA5-21040 can be used with blocking peptide PEP-1154.

TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predomitly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kappa-B activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.
Specifications

Specifications

TRIP6
Polyclonal
Unconjugated
TRIP6
Liquid
TRIP6
A 15 amino acid peptide near the center of human TRIP6.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q15654, Q9Z1Y4
tcag7.1300, OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1; OPA-interacting protein 1; TR-interacting protein 6; thyroid hormone receptor interacting protein 6; thyroid receptor-interacting protein 6; zyxin related protein 1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
22051, 7205
Documents
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