TRIP6 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521040
A suggested positive control is EL4 cell lysate. PA5-21040 can be used with blocking peptide PEP-1154.TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predomitly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-kappa-B activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.
|A 15 amino acid peptide near the center of human TRIP6.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|tcag7.1300, OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1; OPA-interacting protein 1; TR-interacting protein 6; thyroid hormone receptor interacting protein 6; thyroid receptor-interacting protein 6; zyxin related protein 1|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok