TRPM2 Rabbit anti-Mouse, Rat, DyLight® 650, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522877
DescriptionTRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
|Synthetic peptide made to a C-terminal portion of the rat protein (within residues 1430-1508).|
|Antigen affinity chromatography|
|Immunohistochemistry, Western Blot|
|sodium borate with no preservative|
|EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7, LTrpC-2, estrogen-responsive element-associated gene 1 protein, long transient receptor potential channel 2, transient receptor potential cation channel subfamily M member 2, transient receptor potential channel 7|
|4° C, store in dark|
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