Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

TRPA1 Rabbit anti-Guinea Pig, Human, Mouse, HRP, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522834

Catalog No. PIPA522834


Add to cart

Description

Description

The target sequence has 69% sequence homology with rat. Suggested positive control: human brain membrane fraction.

TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. TRPA1 is a transformation -associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation. The structure of TRPA1 is highly related to both the protein ankyrin and transmembrane proteins. The specific function of TRPA1 has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
Specifications

Specifications

TRPA1
Polyclonal
HRP
TRPA1
Liquid
TRPA1
A synthetic peptide made to a region within the N-terminus (residues 1-100) of the human TRPA1 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Guinea Pig, Human, Mouse
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
1.1 mg/mL
PBS with no preservative
O75762, Q8BLA8
ANKTM1, ankyrin-like with transmembrane domains 1, ankyrin-like with transmembrane domains protein 1, transformation-sensitive protein p120, transient receptor potential cation channel subfamily A member 1
Rabbit
IgG
100 μL
4° C, store in dark
Primary
100526649, 277328, 8989
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit