TRPA1 Rabbit anti-Guinea Pig, Human, Mouse, HRP, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA522834
The target sequence has 69% sequence homology with rat. Suggested positive control: human brain membrane fraction.TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. TRPA1 is a transformation -associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation. The structure of TRPA1 is highly related to both the protein ankyrin and transmembrane proteins. The specific function of TRPA1 has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
|A synthetic peptide made to a region within the N-terminus (residues 1-100) of the human TRPA1 protein.|
|Antigen affinity chromatography|
|Guinea Pig, Human, Mouse|
|Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
|PBS with no preservative|
|ANKTM1, ankyrin-like with transmembrane domains 1, ankyrin-like with transmembrane domains protein 1, transformation-sensitive protein p120, transient receptor potential cation channel subfamily A member 1|
|4° C, store in dark|
|100526649, 277328, 8989|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok