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TRPC3/TRPC6/TRPC7 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific OSR00065W

Catalog No. PIOSR00065W

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

Reconstitute with 100 μL of distilled water. Centrifuge to remove any insoluble material.

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3 (By similarity). May also be activated by internal calcium store depletion. Abundantly expressed in brain. Concentrated in cerebellar Purkinje cells and sparsely localized in cerebellar granule lyer, pontine nuclei and thalamus. Lower levels detected in other tissues.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TRPC3/TRPC6/TRPC7
Polyclonal
Trpc3
Trpc3, Trpc6, Trpc7, Short transient receptor potential channel 3, Short transient receptor potential channel 6, Short transient receptor potential channel 7, Transient receptor protein 3, Transient receptor protein 6, Transient receptor protein 7
Rabbit
100 μL
Primary
Mouse
Antibody
IgG
Immunohistochemistry, Western Blot
Unconjugated
Q61143, Q9QZC1, Q9WVC5
TRPC3, TRPC6, TRPC7
A synthetic peptide from cytoplasmic loop of mouse TRPC3 conjugated to an immunogenic carrier protein
RUO
22065, 22068, 26946
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Lyophilized
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