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TRPC3/TRPC6/TRPC7 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen OSR00065W

Catalog No. PIOSR00065W


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Description

Description

Reconstitute with 100 µL of distilled water. Centrifuge to remove any insoluble material.

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3 (By similarity). May also be activated by internal calcium store depletion. Abundantly expressed in brain. Concentrated in cerebellar Purkinje cells and sparsely localized in cerebellar granule lyer, pontine nuclei and thalamus. Lower levels detected in other tissues.
Specifications

Specifications

TRPC3/TRPC6/TRPC7
Polyclonal
whole serum with no preservative
Q61143, Q9QZC1, Q9WVC5
Trpc3, Trpc6, Trpc7, Short transient receptor potential channel 3, Short transient receptor potential channel 6, Short transient receptor potential channel 7, Transient receptor protein 3, Transient receptor protein 6, Transient receptor protein 7
Rabbit
IgG
RUO
Antibody
Polyclonal
Mouse
Immunohistochemistry, Western Blot
Unconjugated
Trpc3
Lyophilized
TRPC3, TRPC6, TRPC7
A synthetic peptide from cytoplasmic loop of mouse TRPC3 conjugated to an immunogenic carrier protein
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22065, 22068, 26946
Documents
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