TRPC3/TRPC6/TRPC7 Rabbit anti-Mouse, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific OSR00065W
Reconstitute with 100 μL of distilled water. Centrifuge to remove any insoluble material.Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3 (By similarity). May also be activated by internal calcium store depletion. Abundantly expressed in brain. Concentrated in cerebellar Purkinje cells and sparsely localized in cerebellar granule lyer, pontine nuclei and thalamus. Lower levels detected in other tissues.
|Trpc3, Trpc6, Trpc7, Short transient receptor potential channel 3, Short transient receptor potential channel 6, Short transient receptor potential channel 7, Transient receptor protein 3, Transient receptor protein 6, Transient receptor protein 7
|Immunohistochemistry, Western Blot
|Q61143, Q9QZC1, Q9WVC5
|TRPC3, TRPC6, TRPC7
|A synthetic peptide from cytoplasmic loop of mouse TRPC3 conjugated to an immunogenic carrier protein
|22065, 22068, 26946
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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