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TRPC5 Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen OST00054G

Catalog No. PIOST00054G


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Description

Description

Reconstitute with 500 µL of distilled water.

TRPC5 belongs to the transient receptor family. TRPC5 is one of the seven mammalian TRPC (transient receptor potential channel) proteins. The TRPC5 protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. TRPC5 also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). TRPC5 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, or G-protein coupled receptors. TRPC5 has also been shown to be calcium-selective, and may also be activated by intracellular calcium store depletion. Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
Specifications

Specifications

TRPC5
Polyclonal
Unconjugated
TRPC5
Lyophilized
TRPC5
A synthetic peptide from the 4th cytoplasmic domain of human TRPC5
Ammonium sulfate precipitation
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Western Blot
1 mg/mL
Antibody with no preservative
Q9UL62
Short transient receptor potential channel 5, TrpC5, Htrp-5, trp5, TRP5
Sheep
IgG
500 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
7224
Documents
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