Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

TRPM2 Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522218

Catalog No. PIPA522218


Add to cart

Description

Description

PA5-22218 targets TRPM2 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-22218 immunogen is a recombit fragment corresponding to a region within amino acids 181 and 423 of TRPM2 (Uniprot IDNo.O94759). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
Specifications

Specifications

TRPM2
Polyclonal
Unconjugated
TRPM2
Liquid
TRPM2
Recombit fragment corresponding to a region within amino acids 181 and 423 of TRPM2 (Uniprot IDNo.O94759)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry (Paraffin), Western Blot
1.38 mg/mL
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
O94759, E9PTA2
EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7, LTrpC-2, estrogen-responsive element-associated gene 1 protein, long transient receptor potential channel 2, transient receptor potential cation channel subfamily M member 2, transient receptor potential channel 7
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
294329, 7226
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit