Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

TRPM8 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA515507

Catalog No. PIPA515507

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This antibody is predicted to react with rat based on sequence homology.

TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. TRPM8 is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. TRPM8 is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. TRPM8 has an expression pattern within normal human tissues that is mostly restricted to prostate epithelial cells. TRPM8 mRNA expression is at moderate levels in normal prostate tissue and appears to be elevated in prostate cancer. Notably, TRPM8 mRNA was also expressed in a number of nonprostatic primary tumors of breast, colon, lung, and skin origin, whereas transcripts encoding TRPM8 were hardly detected or not detected in the corresponding normal human tissues.
Specifications

Specifications

TRPM8
Polyclonal
PBS with 0.09% sodium azide
Q7Z2W7
Transient receptor potential cation channel subfamily M member 8; Long transient receptor potential channel 6; LTrpC6; Transient receptor potential-p8; Trp-p8; TRPM8
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79054
Immunohistochemistry, Western Blot
Unconjugated
TRPM8
Liquid
TRPM8
KLH conjugated synthetic peptide between 1075-1104 amino acids from the C-terminal region of human TRPM8
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit