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TRPV4 Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen OST00034W

Catalog No. PIOST00034W


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Description

Description

Reconstitute with 100 µL of distilled water.

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

TRPV4
Polyclonal
whole serum with no preservative
Q9HBA0
CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VRL2, VROAC
Sheep
IgG
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Western Blot
Unconjugated
TRPV4
Lyophilized
TRPV4
A synthetic peptide from the 1t cytoplasmic loop of human TRPV4
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
59341
Documents
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