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TRPV4 Rabbit anti-Zebrafish, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen OST00071W

Catalog No. PIOST00071W


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Description

Description

Glycerol (1:1) may be added for additional stability. Reconstitute in 100 µL of sterile water.

TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

TRPV4
Polyclonal
whole serum with no preservative
Lyophilized
TRPV4
A synthetic peptide from zebrafish TRPV4, conjugated to an immunogenic carrier protein
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
557850
Immunohistochemistry, Western Blot
Unconjugated
trpv4
Transient receptor potential cation channel, subfamily V, member 4
Rabbit
IgG
RUO
Antibody
Polyclonal
Zebrafish
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