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Trypsin 2 Mouse anti-Human, Clone: 410322, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524148

Catalog No. PIMA524148


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Description

Description

This antibody does not cross-react with Recombinant human (rh) Trypsin 1 or rhTrypsin 3. This antibody recognizes both the pro and mature forms of rhTrypsin 2. Reconstitute at 0.5 mg/mL in sterile PBS.

Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.
Specifications

Specifications

Trypsin 2
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P07478
PRSS2, Tesp4, TRY8, Trypsinogen 20, Anionic trypsinogen, EC 3.4.21, EC 3.4.21.4, MGC111183, MGC120174, MGC120175, protease serine 2 preproprotein, protease, serine, 2 (trypsin 2), protease, serine, 2, preproprotein, Serine protease 2, TRY2TRY8, TRYP2, trypsin 2, Trypsin II, trypsin-2, trypsinogen 2
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5645
Immunoprecipitation, Western Blot
410322
Unconjugated
PRSS2
Lyophilized
PRSS2
Mouse myeloma cell line NS0-derived recombit human Trypsin 2/PRSS2 Ala16-Ser247
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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