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alpha Tubulin Rabbit anti-Drosophila, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522060

Catalog No. PIPA522060


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Description

Description

PA5-22060 targets Tubulin alpha 1A in ICC, IF, IHC (P), and WB applications and shows reactivity with Drosophila, Human, Rat and mouse samples. The PA5-22060 immunogen is recombit protein fragment contain a sequence corresponding to a region within amino acids 37 and 276 (Q71U36) of alpha Tubulin 1A. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predomitly found in morphologically differentiated neurologic cells.
Specifications

Specifications

alpha Tubulin
Polyclonal
Unconjugated
TUBA1A
Liquid
ALPHATUB84B, TUBA1A
Recombit protein fragment contain a sequence corresponding to a region within amino acids 37 and 276 (Q71U36) of alpha Tubulin 1A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Drosophila, Human, Mouse, Non-human primate, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.25 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
P06603, Q71U36, P68369, P68370
B-ALPHA-1, LIS3, TUBA3, alpha-tubulin 3, hum-a-tub1, hum-a-tub2, tubulin B-alpha-1, tubulin alpha-1A chain, tubulin alpha-3 chain, tubulin, alpha 3, tubulin, alpha, brain-specific
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
22142, 40848, 64158, 7846
Documents
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