β-Tubulin Mouse, Unlabeled, Clone: 5H1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 556321

Catalog No. BDB556321

Description

Tubulin is a highly conserved protein with a molecular weight of ∽50 kD. The self-assembly of tubulin leads to microtubules, hollow cylinders that are one of the major components of the eukaryotic cytoskeleton. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. There are two main classes of tubulin isoforms, α - and β -tubulin, which are usually products of separate genes. Microtubules are made from protofilaments, strings of alternating α - and β -tubulin spaced 4nm apart and pointing in the same direction. Tubulin can be posttranslationally modified in several ways, including phosphorylation, acetylation, glutamylation, and detyrosination. For example, microtubules that turn over slowly tend to be acetylated and detyrosinated.

Specifications

• Antigen: β-Tubulin
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Western Blot
• Clone: 5H1
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 0.1 mg
• Research Discipline: Cell Biology
• Target Species: Bovine, Human, Mouse, Rat
• Isotype: IgM κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.