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alpha/beta Tubulin Rabbit anti-Human, Mouse, Porcine, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA186602

Catalog No. PA186602


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Description

Description

Rabbit anti Porcine tubulin antibody recognizes tubulin, a protein which is the major constituent of microtubules.

Tubulin protein is the major constituent of microtubules. Tubulin is a dimer of alpha and beta chains, which binds two molecules of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. There are at least six isotypes of both alpha- and beta- tubulin in human cells, which are distinguished by slightly different amino acid sequences and encoded by a large, multigene family that has been highly conserved throughout evolution. Although the most important functions of microtubules in proliferative cells are through their actions as components of the mitotic spindle, they are also involved in many other essential functions throughout the cell cycle of both maligt and nonmaligt cells. Anti-microtubule agents including Vinca alkaloids and taxanes may disrupt many of these essential functions.
Specifications

Specifications

alpha/beta Tubulin
Polyclonal
Unconjugated
TUBA1A
Liquid
Rabbit
IgG
500 μL
4°C or -20°C if preferred
Primary
100135051, 203068, 22142, 64158, 733686, 7846
ELISA, Western Blot
5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P07437, Q71U36, P68369, P02550, Q767L7, P68370
TUBA1A, TUBB
Purified porcine brain tubulin.
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Porcine, Rat
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