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TEM8 Mouse anti-Human, Clone: 200C1339 (SB20), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA141059

Catalog No. 01-676-457


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Description

Description

Suggested positive control: TEM8 transfected cell lysate.

Recently, using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9). Based on TEM8s interaction with the C5 domain of collagen a3(VI), a protein also preferentially expressed in tumor endothelium, it is thought that TEM8 plays an important role in tumor angiogenesis.
Specifications

Specifications

TEM8
Monoclonal
1.0 mg/mL
PBS with 0.05% sodium azide
Q9H6X2
TEM8
Mouse
IgG1
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
84168
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
200C1339 (SB20)
Unconjugated
ANTXR1
Liquid
ANTXR1
Synthetic peptide corresponding to residues 481-497 of human TEM8.
Protein G
RUO
Antibody
Monoclonal
Human
Documents
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