TWEAK Mouse anti-Human, Clone: 173830, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523783
In sandwich ELISAs, approximately 15% reactivity with recombit mouse TWEAK is observed and no cross-reactivity with recombit human (rh) BAFF, rhEDA-A2, rhLIGHT, rhFas Ligand, rhGITR Ligand, rhLT alpha 1 beta 2, rhLT alpha 2 beta 1, rhOX40 Ligand, rhTNF-alpha, rhTRANCE, rhTRAIL, rh4-1BB, or rhAPRIL is observed. Reconstitute at 0.5 mg/mL in sterile PBS.TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
|PBS with 5% trehalose and No Preservative|
|UNQ181/PRO207, APO3L, DR3LG, TWEAK, APO3 ligand, APO3/DR3 ligand, TNF-related WEAK inducer of apoptosis, tumor necrosis factor ligand superfamily member 12|
|-20° C, Avoid Freeze/Thaw Cycles|
|E. coli-derived recombit human TWEAK/TNFSF12 Arg93-His249|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok