Tyrosinase Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527324
PA5-27324 targets Tyrosinase in WB applications and shows reactivity with Human samples. The PA5-27324 immunogen is recombit fragment corresponding to a region within amino acids 225 and 489 of Human Tyrosinase. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3 ft. half of this gene.
|Recombit fragment corresponding to a region within amino acids 225 and 489 of Human Tyrosinase|
|Antigen affinity chromatography|
|0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7|
|CMM8, OCA1A, OCAIA, SHEP3, LB24-AB, SK29-AB, monophenol monooxygenase, tumor rejection antigen AB, tyrosinase|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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