YARS Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527434
PA5-27434 targets Tyrosyl tRNA synthetase in IF and WB applications and shows reactivity with Human samples. The PA5-27434 immunogen is recombit fragment corresponding to a region within amino acids 307 and 528 of Human Tyrosyl tRNA synthetase. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
|Recombit fragment corresponding to a region within amino acids 307 and 528 of Human Tyrosyl tRNA synthetase|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CMTDIC, TYRRS, YRS, YTS, tyrosine tRNA ligase 1, cytoplasmic, tyrosine--tRNA ligase, cytoplasmic, tyrosyl--tRNA ligase, tyrosyl-tRNA synthetase, cytoplasmic|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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