Ubiquilin 1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA512079

Catalog No. PIPA512079

Description

This antibody is predicted to react with rat based on sequence homology.

PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer′s and Parkinson′s disease.

Specifications

• Antigen: Ubiquilin 1
• Classification: Polyclonal
• Gene: UBQLN1
• Gene Alias: Ubiquilin 1; Protein linking IAP with cytoskeleton-1; PLIC-1; hPLIC-1; UBQLN1
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 29979, 56085
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q9UMX0, Q8R317
• Gene Symbols: UBQLN1
• Immunogen: KLH conjugated synthetic peptide between 296-326 amino acids from the central region of human Ubiquilin1
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG