Ubiquitin Rabbit anti-Canine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA1187
PA1-187 detects both the ubiquitin monomer as well as poly-ubiquitinated proteins of various molecular weights.Ubiquitin is a conserved 76 amino acid polypeptide and can affect proteasomal degradation of the protein it is bound to, or mediate interactions with other proteins related to post-translational modifications. The degradation of cellular regulatory proteins by the Uubiquitin pathway is important as it controls the cellular growth and proliferation. Ubiquitin-dependent proteolysis occurs after a covalent attachment of the peptide to a lysine residue of a protein, which involves three enzymatic reactions: E1, E2 and E3. The first reaction involves ubiquitin-activating enzyme. The third reaction uses enzyme ubiquitin ligase (E3) to transfer the activated ubiquitin from E2 to a lysine residue on a protein, or directly transfers the ubiquitin from E2 to the substrate.
|Canine, Human, Mouse, Non-human primate, Rat|
|PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide|
|P0CG47, P62979, P0CG49, P62983, P0CG51, P62982|
|Ubiquitin B, Polyubiquitin B, polyubiquitin-B, ubiquitin|
|100912032, 192255, 22187, 474599, 479513, 6233, 7314, 78294|
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