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Ubiquitin Rabbit anti-Canine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1187

Catalog No. PIPA1187


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Description

Description

PA1-187 detects both the ubiquitin monomer as well as poly-ubiquitinated proteins of various molecular weights.

Ubiquitin is a conserved 76 amino acid polypeptide and can affect proteasomal degradation of the protein it is bound to, or mediate interactions with other proteins related to post-translational modifications. The degradation of cellular regulatory proteins by the Uubiquitin pathway is important as it controls the cellular growth and proliferation. Ubiquitin-dependent proteolysis occurs after a covalent attachment of the peptide to a lysine residue of a protein, which involves three enzymatic reactions: E1, E2 and E3. The first reaction involves ubiquitin-activating enzyme. The third reaction uses enzyme ubiquitin ligase (E3) to transfer the activated ubiquitin from E2 to a lysine residue on a protein, or directly transfers the ubiquitin from E2 to the substrate.
Specifications

Specifications

Ubiquitin
Polyclonal
Unconjugated
UBB
Liquid
RPS27A, UBB
Full-length monoubiqutin
Protein G
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Non-human primate, Rat
Western Blot
1 mg/mL
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
P0CG47, P62979, P0CG49, P62983, P0CG51, P62982
Ubiquitin B, Polyubiquitin B, polyubiquitin-B, ubiquitin
Rabbit
IgG
100 μg
-20°C
Primary
100912032, 192255, 22187, 474599, 479513, 6233, 7314, 78294
Documents
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